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Arachidonic Acid Metabolism Controls Macrophage Alternative Activation Through Regulating Oxidative Phosphorylation in PPARγ Dependent Manner

Macrophage polarization is mainly steered by metabolic reprogramming in the tissue microenvironment, thus leading to distinct outcomes of various diseases. However, the role of lipid metabolism in the regulation of macrophage alternative activation is incompletely understood. Using human THP-1 and m...

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Detalles Bibliográficos
Autores principales: Xu, Miao, Wang, Xiaohong, Li, Yongning, Geng, Xue, Jia, Xudong, Zhang, Lishi, Yang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211451/
https://www.ncbi.nlm.nih.gov/pubmed/34149684
http://dx.doi.org/10.3389/fimmu.2021.618501