Cargando…
Arachidonic Acid Metabolism Controls Macrophage Alternative Activation Through Regulating Oxidative Phosphorylation in PPARγ Dependent Manner
Macrophage polarization is mainly steered by metabolic reprogramming in the tissue microenvironment, thus leading to distinct outcomes of various diseases. However, the role of lipid metabolism in the regulation of macrophage alternative activation is incompletely understood. Using human THP-1 and m...
Autores principales: | Xu, Miao, Wang, Xiaohong, Li, Yongning, Geng, Xue, Jia, Xudong, Zhang, Lishi, Yang, Hui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211451/ https://www.ncbi.nlm.nih.gov/pubmed/34149684 http://dx.doi.org/10.3389/fimmu.2021.618501 |
Ejemplares similares
-
Alpha-Tocopherol prevents esophageal squamous cell carcinoma by modulating PPARγ-Akt signaling pathway at the early stage of carcinogenesis
por: Xu, Miao, et al.
Publicado: (2017) -
Combination Therapy of PPARγ Ligands and Inhibitors of Arachidonic Acid in Lung
Cancer
por: Tauler, Jordi, et al.
Publicado: (2008) -
S100A4 enhances protumor macrophage polarization by control of PPAR-γ-dependent induction of fatty acid oxidation
por: Liu, Shuangqing, et al.
Publicado: (2021) -
Procyanidin B2 Activates PPARγ to Induce M2 Polarization in Mouse Macrophages
por: Tian, Ying, et al.
Publicado: (2019) -
Influenza virus causes lung immunopathology through down-regulating PPARγ activity in macrophages
por: Zhang, Hongbo, et al.
Publicado: (2022)