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PFKFB4 Overexpression Facilitates Proliferation by Promoting the G1/S Transition and Is Associated with a Poor Prognosis in Triple-Negative Breast Cancer

BACKGROUND: 6-Phosphofructo-2-kinase/fructose-2,6-biphosphate-4 (PFKFB4) is a key factor that plays an important role in tumorigenesis. However, its role in triple-negative breast cancer (TNBC) progression needs to be further validated. We investigated whether PFKFB4 is directly involved in the onco...

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Detalles Bibliográficos
Autores principales: Cai, Yu-Chen, Yang, Hang, Shan, Hong-Bo, Su, Hui-Fang, Jiang, Wen-Qi, Shi, Yan-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211511/
https://www.ncbi.nlm.nih.gov/pubmed/34211613
http://dx.doi.org/10.1155/2021/8824589