Predicting the Most Deleterious Missense Nonsynonymous Single-Nucleotide Polymorphisms of Hennekam Syndrome-Causing CCBE1 Gene, In Silico Analysis

Hennekam lymphangiectasia-lymphedema syndrome has been linked to single-nucleotide polymorphisms in the CCBE1 (collagen and calcium-binding EGF domains 1) gene. Several bioinformatics methods were used to find the most dangerous nsSNPs that could affect CCBE1 structure and function. Using state-of-t...

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Detalles Bibliográficos
Autores principales: Shinwari, Khyber, Guojun, Liu, Deryabina, Svetlana S., Bolkov, Mikhail A., Tuzankina, Irina A., Chereshnev, Valery A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211529/
https://www.ncbi.nlm.nih.gov/pubmed/34234628
http://dx.doi.org/10.1155/2021/6642626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211529/
https://www.ncbi.nlm.nih.gov/pubmed/34234628
http://dx.doi.org/10.1155/2021/6642626

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