A phase I/II study of bevacizumab, irinotecan and erlotinib in children with progressive diffuse intrinsic pontine glioma

INTRODUCTION: This study investigates the safety, tolerability, and preliminary efficacy of combined treatment with VEGF inhibitor bevacizumab, topoisomerase I inhibitor irinotecan, and EGFR inhibitor erlotinib in children with progressive diffuse intrinsic pontine glioma (DIPG). METHODS: Biweekly b...

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Detalles Bibliográficos
Autores principales: El-Khouly, Fatma E., Veldhuijzen van Zanten, Sophie E. M., Jansen, Marc H. A., Bakker, Dewi P., Sanchez Aliaga, Esther, Hendrikse, N. Harry, Vandertop, W. Peter, van Vuurden, Dannis G., Kaspers, Gertjan J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211596/
https://www.ncbi.nlm.nih.gov/pubmed/33963476
http://dx.doi.org/10.1007/s11060-021-03763-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211596/
https://www.ncbi.nlm.nih.gov/pubmed/33963476
http://dx.doi.org/10.1007/s11060-021-03763-1

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