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Utility of BMI-1 and NANOG expression levels in survival prediction of pediatric acute lymphoblastic leukemia

BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common malignancy in children characterized by the overproduction and accumulation of immature lymphoid cells in the bone marrow and peripheral blood. The BMI-1 is an important component of the Polycomb Repressive Complex-1 (PRC1). It is an...

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Detalles Bibliográficos
Autores principales: Abdel-khalek, Sara, Saleh, Layla M., Abdel-Aziz, Sherin, Hyder, Ayman, Abdel-ghaffar, Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211619/
https://www.ncbi.nlm.nih.gov/pubmed/32278650
http://dx.doi.org/10.1016/j.htct.2020.01.002