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Polymorphisms in the heme oxygenase-1 and bone morphogenetic protein receptor type 1b genes and estimated glomerular filtration rate in Brazilian sickle cell anemia patients

INTRODUCTION: Mutations affecting genes involved in oxidative and signaling pathways may be associated with kidney disease in sickle cell anemia. We determined the allele and genotype frequencies of some polymorphisms in the promoter regions of the Heme Oxygenase-1 (HMOX1) [rs2071746 (A > T) and...

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Detalles Bibliográficos
Autores principales: Chinedu, Okeke, Tonassé, Wouitchékpo Vincent, Albuquerque, Dulcinéia Martins, Domingos, Igor de Farias, Araújo, Aderson da Silva, Bezerra, Marcos André Cavalcanti, Sonati, Maria de Fátima, Santos, Magnun Nueldo Nunes dos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211626/
https://www.ncbi.nlm.nih.gov/pubmed/32461055
http://dx.doi.org/10.1016/j.htct.2020.01.009