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A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre

Following implantation, the human embryo undergoes major morphogenetic transformations that establish the future body plan. While the molecular events underpinning this process are established in mice, they remain unknown in humans. Here we characterise key events of human embryo morphogenesis, in t...

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Detalles Bibliográficos
Autores principales: Molè, Matteo A., Coorens, Tim H. H., Shahbazi, Marta N., Weberling, Antonia, Weatherbee, Bailey A. T., Gantner, Carlos W., Sancho-Serra, Carmen, Richardson, Lucy, Drinkwater, Abbie, Syed, Najma, Engley, Stephanie, Snell, Philip, Christie, Leila, Elder, Kay, Campbell, Alison, Fishel, Simon, Behjati, Sam, Vento-Tormo, Roser, Zernicka-Goetz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211662/
https://www.ncbi.nlm.nih.gov/pubmed/34140473
http://dx.doi.org/10.1038/s41467-021-23758-w