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Unfolded protein response triggers differential apoptotic mechanisms in ovaries and early embryos exposed to maternal type 1 diabetes

Diabetes mellitus (DM) has profound effects on the female mammalian reproductive system, and early embryonic development, reducing female reproductive outcomes and inducing developmental programming in utero. However, the underlying cellular and molecular mechanisms remain poorly defined. Accumulati...

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Detalles Bibliográficos
Autores principales: Okan, Aslı, Demir, Necdet, Sozen, Berna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211688/
https://www.ncbi.nlm.nih.gov/pubmed/34140543
http://dx.doi.org/10.1038/s41598-021-92093-3