An ACE2 Triple Decoy that neutralizes SARS-CoV-2 shows enhanced affinity for virus variants

The SARS-CoV-2 variants replacing the first wave strain pose an increased threat by their potential ability to escape pre-existing humoral protection. An angiotensin converting enzyme 2 (ACE2) decoy that competes with endogenous ACE2 for binding of the SARS-CoV-2 spike receptor binding domain (S RBD...

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Detalles Bibliográficos
Autores principales: Tanaka, Shiho, Nelson, Gard, Olson, C. Anders, Buzko, Oleksandr, Higashide, Wendy, Shin, Annie, Gonzalez, Marcos, Taft, Justin, Patel, Roosheel, Buta, Sofija, Richardson, Ashley, Bogunovic, Dusan, Spilman, Patricia, Niazi, Kayvan, Rabizadeh, Shahrooz, Soon-Shiong, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211782/
https://www.ncbi.nlm.nih.gov/pubmed/34140558
http://dx.doi.org/10.1038/s41598-021-91809-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211782/
https://www.ncbi.nlm.nih.gov/pubmed/34140558
http://dx.doi.org/10.1038/s41598-021-91809-9

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