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Machine learning differentiates enzymatic and non-enzymatic metals in proteins

Metalloenzymes are 40% of all enzymes and can perform all seven classes of enzyme reactions. Because of the physicochemical similarities between the active sites of metalloenzymes and inactive metal binding sites, it is challenging to differentiate between them. Yet distinguishing these two classes...

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Detalles Bibliográficos
Autores principales: Feehan, Ryan, Franklin, Meghan W., Slusky, Joanna S. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211803/
https://www.ncbi.nlm.nih.gov/pubmed/34140507
http://dx.doi.org/10.1038/s41467-021-24070-3