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Kinetic mechanism of Na(+)-coupled aspartate transport catalyzed by Glt(Tk)

It is well-established that the secondary active transporters Glt(Tk) and Glt(Ph) catalyze coupled uptake of aspartate and three sodium ions, but insight in the kinetic mechanism of transport is fragmentary. Here, we systematically measured aspartate uptake rates in proteoliposomes containing purifi...

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Detalles Bibliográficos
Autores principales: Trinco, Gianluca, Arkhipova, Valentina, Garaeva, Alisa A., Hutter, Cedric A. J., Seeger, Markus A., Guskov, Albert, Slotboom, Dirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211817/
https://www.ncbi.nlm.nih.gov/pubmed/34140623
http://dx.doi.org/10.1038/s42003-021-02267-y