Hypoxia-induced SETX links replication stress with the unfolded protein response

Tumour hypoxia is associated with poor patient prognosis and therapy resistance. A unique transcriptional response is initiated by hypoxia which includes the rapid activation of numerous transcription factors in a background of reduced global transcription. Here, we show that the biological response...

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Detalles Bibliográficos
Autores principales: Ramachandran, Shaliny, Ma, Tiffany S., Griffin, Jon, Ng, Natalie, Foskolou, Iosifina P., Hwang, Ming-Shih, Victori, Pedro, Cheng, Wei-Chen, Buffa, Francesca M., Leszczynska, Katarzyna B., El-Khamisy, Sherif F., Gromak, Natalia, Hammond, Ester M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211819/
https://www.ncbi.nlm.nih.gov/pubmed/34140498
http://dx.doi.org/10.1038/s41467-021-24066-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211819/
https://www.ncbi.nlm.nih.gov/pubmed/34140498
http://dx.doi.org/10.1038/s41467-021-24066-z

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