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Molecular mechanism of calcium induced trimerization of C1q-like domain of otolin-1 from human and zebrafish

The C1q superfamily includes proteins involved in innate immunity, insulin sensitivity, biomineralization and more. Among these proteins is otolin-1, which is a collagen-like protein that forms a scaffold for the biomineralization of inner ear stones in vertebrates. The globular C1q-like domain (gC1...

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Detalles Bibliográficos
Autores principales: Hołubowicz, Rafał, Ożyhar, Andrzej, Dobryszycki, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211825/
https://www.ncbi.nlm.nih.gov/pubmed/34140580
http://dx.doi.org/10.1038/s41598-021-92129-8