The LDL receptor binding domain of apolipoprotein E directs the relative orientation of its C-terminal segment in reconstituted nascent HDL

Apolipoprotein E (apoE) (299 residues) is a highly helical protein that plays a critical role in cholesterol homeostasis. It comprises a four-helix bundle N-terminal (NT) and a C-terminal (CT) domain that can exist in lipid-free and lipid-associated states. In humans, there are two major apoE isofor...

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Detalles Bibliográficos
Autores principales: Kothari, S., Bala, N., Patel, A.B., Donovan, A., Narayanaswami, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211829/
https://www.ncbi.nlm.nih.gov/pubmed/33831404
http://dx.doi.org/10.1016/j.bbamem.2021.183618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211829/
https://www.ncbi.nlm.nih.gov/pubmed/33831404
http://dx.doi.org/10.1016/j.bbamem.2021.183618

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