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Model-based prediction of spatial gene expression via generative linear mapping

Decoding spatial transcriptomes from single-cell RNA sequencing (scRNA-seq) data has become a fundamental technique for understanding multicellular systems; however, existing computational methods lack both accuracy and biological interpretability due to their model-free frameworks. Here, we introdu...

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Detalles Bibliográficos
Autores principales: Okochi, Yasushi, Sakaguchi, Shunta, Nakae, Ken, Kondo, Takefumi, Naoki, Honda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211835/
https://www.ncbi.nlm.nih.gov/pubmed/34140477
http://dx.doi.org/10.1038/s41467-021-24014-x