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Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases

Fibrotic skin disease represents a major global healthcare burden, characterized by fibroblast hyperproliferation and excessive accumulation of extracellular matrix. Fibroblasts are found to be heterogeneous in multiple fibrotic diseases, but fibroblast heterogeneity in fibrotic skin diseases is not...

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Detalles Bibliográficos
Autores principales: Deng, Cheng-Cheng, Hu, Yong-Fei, Zhu, Ding-Heng, Cheng, Qing, Gu, Jing-Jing, Feng, Qing-Lan, Zhang, Li-Xue, Xu, Ying-Ping, Wang, Dong, Rong, Zhili, Yang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211847/
https://www.ncbi.nlm.nih.gov/pubmed/34140509
http://dx.doi.org/10.1038/s41467-021-24110-y