Cargando…
Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases
Fibrotic skin disease represents a major global healthcare burden, characterized by fibroblast hyperproliferation and excessive accumulation of extracellular matrix. Fibroblasts are found to be heterogeneous in multiple fibrotic diseases, but fibroblast heterogeneity in fibrotic skin diseases is not...
Autores principales: | Deng, Cheng-Cheng, Hu, Yong-Fei, Zhu, Ding-Heng, Cheng, Qing, Gu, Jing-Jing, Feng, Qing-Lan, Zhang, Li-Xue, Xu, Ying-Ping, Wang, Dong, Rong, Zhili, Yang, Bin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211847/ https://www.ncbi.nlm.nih.gov/pubmed/34140509 http://dx.doi.org/10.1038/s41467-021-24110-y |
Ejemplares similares
-
Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease
por: Shaw, Tanya J, et al.
Publicado: (2020) -
Kinase inhibitors fail to induce mesenchymal-epithelial transition in fibroblasts from fibrotic lung tissue
por: Xu, Xuefeng, et al.
Publicado: (2020) -
Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the heterogeneity of cancer-associated fibroblasts in TNBC
por: Wu, Xiaoqing, et al.
Publicado: (2023) -
Human Gingival Fibroblasts Display a Non-Fibrotic Phenotype Distinct from Skin Fibroblasts in Three-Dimensional Cultures
por: Mah, Wesley, et al.
Publicado: (2014) -
Fibroblasts are not just fibroblasts: clear differences between dermal and pulmonary fibroblasts’ response to fibrotic growth factors
por: Madsen, Sofie Falkenløve, et al.
Publicado: (2023)