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Normal cells repel WWOX-negative or -dysfunctional cancer cells via WWOX cell surface epitope 286-299
Metastatic cancer cells are frequently deficient in WWOX protein or express dysfunctional WWOX (designated WWOXd). Here, we determined that functional WWOX-expressing (WWOXf) cells migrate collectively and expel the individually migrating WWOXd cells. For return, WWOXd cells induces apoptosis of WWO...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211909/ https://www.ncbi.nlm.nih.gov/pubmed/34140629 http://dx.doi.org/10.1038/s42003-021-02271-2 |