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Normal cells repel WWOX-negative or -dysfunctional cancer cells via WWOX cell surface epitope 286-299

Metastatic cancer cells are frequently deficient in WWOX protein or express dysfunctional WWOX (designated WWOXd). Here, we determined that functional WWOX-expressing (WWOXf) cells migrate collectively and expel the individually migrating WWOXd cells. For return, WWOXd cells induces apoptosis of WWO...

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Detalles Bibliográficos
Autores principales: Chen, Yu-An, Sie, Yong-Da, Liu, Tsung-Yun, Kuo, Hsiang-Ling, Chou, Pei-Yi, Chen, Yu-Jie, Lee, Kuan-Ting, Chen, Pin-Jun, Chen, Shur-Tzu, Chang, Nan-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211909/
https://www.ncbi.nlm.nih.gov/pubmed/34140629
http://dx.doi.org/10.1038/s42003-021-02271-2