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Stress Granule-Mediated Oxidized RNA Decay in P-Body: Hypothetical Role of ADAR1, Tudor-SN, and STAU1

Reactive oxygen species (ROS) generated under oxidative stress (OS) cause oxidative damage to RNA. Recent studies have suggested a role for oxidized RNA in several human disorders. Under the conditions of oxidative stress, mRNAs released from polysome dissociation accumulate and initiate stress gran...

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Detalles Bibliográficos
Autores principales: Alluri, Ravi Kumar, Li, Zhongwei, McCrae, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211916/
https://www.ncbi.nlm.nih.gov/pubmed/34150849
http://dx.doi.org/10.3389/fmolb.2021.672988