Primaquine Diphosphate, a Known Antimalarial Drug, Blocks Vascular Leakage Acting Through Junction Stabilization

Endothelial barrier integrity is important for vascular homeostasis, and hyperpermeability participates in the progression of many pathological states, such as diabetic retinopathy, ischemic stroke, chronic bowel disease, and inflammatory disease. Here, using drug repositioning, we discovered that p...

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Detalles Bibliográficos
Autores principales: Noh, Minyoung, Zhang, Haiying, Kim, Hyejeong, Park, Songyi, Kim, Young-Myeong, Kwon, Young-Guen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211987/
https://www.ncbi.nlm.nih.gov/pubmed/34149436
http://dx.doi.org/10.3389/fphar.2021.695009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211987/
https://www.ncbi.nlm.nih.gov/pubmed/34149436
http://dx.doi.org/10.3389/fphar.2021.695009

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