Cargando…

Combined Effects of Exercise and Denosumab Treatment on Local Failure in Post-menopausal Osteoporosis–Insights from Bone Remodelling Simulations Accounting for Mineralisation and Damage

Denosumab has been shown to increase bone mineral density (BMD) and reduce the fracture risk in patients with post-menopausal osteoporosis (PMO). Increase in BMD is linked with an increase in bone matrix mineralisation due to suppression of bone remodelling. However, denosumab anti-resorptive action...

Descripción completa

Detalles Bibliográficos
Autores principales: Martínez-Reina, Javier, Calvo-Gallego, José L., Pivonka, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212042/
https://www.ncbi.nlm.nih.gov/pubmed/34150724
http://dx.doi.org/10.3389/fbioe.2021.635056