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GRMT: Generative Reconstruction of Mutation Tree From Scratch Using Single-Cell Sequencing Data

Single-cell sequencing (SCS) now promises the landscape of genetic diversity at single cell level, and is particularly useful to reconstruct the evolutionary history of tumor. There are multiple types of noise that make the SCS data notoriously error-prone, and significantly complicate tumor tree re...

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Detalles Bibliográficos
Autores principales: Yu, Zhenhua, Liu, Huidong, Du, Fang, Tang, Xiaofen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212059/
https://www.ncbi.nlm.nih.gov/pubmed/34149820
http://dx.doi.org/10.3389/fgene.2021.692964