A Staphylococcus aureus clpX Mutant Used as a Unique Screening Tool to Identify Cell Wall Synthesis Inhibitors that Reverse β-Lactam Resistance in MRSA

Staphylococcus aureus is a leading cause of bacterial infections world-wide. Staphylococcal infections are preferentially treated with β-lactam antibiotics, however, methicillin-resistant S. aureus (MRSA) strains have acquired resistance to this superior class of antibiotics. We have developed a gro...

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Detalles Bibliográficos
Autores principales: Bæk, Kristoffer T., Jensen, Camilla, Farha, Maya A., Nielsen, Tobias K., Paknejadi, Ervin, Mebus, Viktor H., Vestergaard, Martin, Brown, Eric D., Frees, Dorte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212132/
https://www.ncbi.nlm.nih.gov/pubmed/34150853
http://dx.doi.org/10.3389/fmolb.2021.691569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212132/
https://www.ncbi.nlm.nih.gov/pubmed/34150853
http://dx.doi.org/10.3389/fmolb.2021.691569

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