Causal interactions from proteomic profiles: Molecular data meet pathway knowledge

We present a computational method to infer causal mechanisms in cell biology by analyzing changes in high-throughput proteomic profiles on the background of prior knowledge captured in biochemical reaction knowledge bases. The method mimics a biologist's traditional approach of explaining chang...

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Detalles Bibliográficos
Autores principales: Babur, Özgün, Luna, Augustin, Korkut, Anil, Durupinar, Funda, Siper, Metin Can, Dogrusoz, Ugur, Vaca Jacome, Alvaro Sebastian, Peckner, Ryan, Christianson, Karen E., Jaffe, Jacob D., Spellman, Paul T., Aslan, Joseph E., Sander, Chris, Demir, Emek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212145/
https://www.ncbi.nlm.nih.gov/pubmed/34179843
http://dx.doi.org/10.1016/j.patter.2021.100257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212145/
https://www.ncbi.nlm.nih.gov/pubmed/34179843
http://dx.doi.org/10.1016/j.patter.2021.100257

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