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Causal interactions from proteomic profiles: Molecular data meet pathway knowledge
We present a computational method to infer causal mechanisms in cell biology by analyzing changes in high-throughput proteomic profiles on the background of prior knowledge captured in biochemical reaction knowledge bases. The method mimics a biologist's traditional approach of explaining chang...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212145/ https://www.ncbi.nlm.nih.gov/pubmed/34179843 http://dx.doi.org/10.1016/j.patter.2021.100257 |