Long non-coding RNA MEG3 mediates the miR-149-3p/FOXP3 axis by reducing p53 ubiquitination to exert a suppressive effect on regulatory T cell differentiation and immune escape in esophageal cancer

BACKGROUND: Long non-coding RNA (lncRNA) maternally expressed gene 3 (MEG3) has been implicated in the progression of esophageal cancer (EC). However, the specific mechanism of the involvement of MEG3 in EC development in relation to the regulation of immune escape remains uncertain. Thus, the aim o...

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Detalles Bibliográficos
Autores principales: Xu, Qi-Rong, Tang, Jian, Liao, Hong-Ying, Yu, Ben-Tong, He, Xiang-Yuan, Zheng, Yu-Zhen, Liu, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212454/
https://www.ncbi.nlm.nih.gov/pubmed/34140005
http://dx.doi.org/10.1186/s12967-021-02907-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212454/
https://www.ncbi.nlm.nih.gov/pubmed/34140005
http://dx.doi.org/10.1186/s12967-021-02907-1

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