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Statistical genetics and polygenic risk score for precision medicine

The prediction of disease risks is an essential part of personalized medicine, which includes early disease detection, prevention, and intervention. The polygenic risk score (PRS) has become the standard for quantifying genetic liability in predicting disease risks. PRS utilizes single-nucleotide po...

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Detalles Bibliográficos
Autores principales: Konuma, Takahiro, Okada, Yukinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212479/
https://www.ncbi.nlm.nih.gov/pubmed/34140035
http://dx.doi.org/10.1186/s41232-021-00172-9