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IMI2-PainCare-BioPain-RCT3: a randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by electroencephalography (EEG)

BACKGROUND: IMI2-PainCare-BioPain-RCT3 is one of four similarly designed clinical studies aiming at profiling a set of functional biomarkers of drug effects on the nociceptive system that could serve to accelerate the future development of analgesics, by providing a quantitative understanding betwee...

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Detalles Bibliográficos
Autores principales: Mouraux, André, Bloms-Funke, Petra, Boesl, Irmgard, Caspani, Ombretta, Chapman, Sonya C., Di Stefano, Giulia, Finnerup, Nanna Brix, Garcia-Larrea, Luis, Goetz, Marcus, Kostenko, Anna, Pelz, Bernhard, Pogatzki-Zahn, Esther, Schubart, Karin, Stouffs, Alexandre, Truini, Andrea, Tracey, Irene, Troconiz, Iñaki F., Van Niel, Johannes, Vela, Jose Miguel, Vincent, Katy, Vollert, Jan, Wanigasekera, Vishvarani, Wittayer, Matthias, Phillips, Keith G., Treede, Rolf-Detlef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212499/
https://www.ncbi.nlm.nih.gov/pubmed/34140041
http://dx.doi.org/10.1186/s13063-021-05272-y