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Circ-SPG11 knockdown hampers IL-1β-induced osteoarthritis progression via targeting miR-337-3p/ADAMTS5

BACKGROUND: Osteoarthritis (OA) is responsible for the impotent disability in old people. Circular RNA (circRNA) has been reported to be related to the development of diseases. The lack of research on the role of circRNA spastic paraplegia 11 (circ-SPG11) results in conducting this study. METHODS: T...

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Detalles Bibliográficos
Autores principales: Liu, Yongqiang, Li, Qian, Gao, Zhida, Lei, Fang, Gao, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212518/
https://www.ncbi.nlm.nih.gov/pubmed/34140036
http://dx.doi.org/10.1186/s13018-021-02526-y