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Real-world effectiveness of early intervention with fixed-dose tiotropium/olodaterol vs tiotropium in Japanese patients with COPD: a high-dimensional propensity score–matched cohort analysis

BACKGROUND: Escalation to triple therapy (long-acting muscarinic antagonist/β(2)-agonist, inhaled corticosteroid [ICS]) in chronic obstructive pulmonary disorder (COPD) is recommended for patients on LAMA/LABA combinations with frequent exacerbations and severe symptoms. An extended time-to-escalati...

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Detalles Bibliográficos
Autores principales: Muro, Shigeo, Suzuki, Masaru, Nakamura, Shuhei, Wang, Jocelyn Ruoyi, Garry, Elizabeth M., Sakamoto, Wataru, de Souza, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212527/
https://www.ncbi.nlm.nih.gov/pubmed/34140019
http://dx.doi.org/10.1186/s12931-021-01776-y