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The genomes of precision edited cloned calves show no evidence for off-target events or increased de novo mutagenesis

BACKGROUND: Animal health and welfare are at the forefront of public concern and the agricultural sector is responding by prioritising the selection of welfare-relevant traits in their breeding schemes. In some cases, welfare-enhancing traits such as horn-status (i.e., polled) or diluted coat colour...

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Detalles Bibliográficos
Autores principales: Jivanji, Swati, Harland, Chad, Cole, Sally, Brophy, Brigid, Garrick, Dorian, Snell, Russell, Littlejohn, Mathew, Laible, Götz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212539/
https://www.ncbi.nlm.nih.gov/pubmed/34139989
http://dx.doi.org/10.1186/s12864-021-07804-x