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Melatonin Attenuates Chromium (VI)-Induced Spermatogonial Stem Cell/Progenitor Mitophagy by Restoration of METTL3-Mediated RNA N(6)-Methyladenosine Modification

Spermatogonial stem cells (SSCs) are the basis of spermatogenesis, and any damage to SSCs may result in spermatogenic disorder and male infertility. Chromium (Cr) (VI) is a proven toxin, mutagen, and carcinogen, perpetually detrimental to environmental organisms due to its intricate and enduring det...

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Detalles Bibliográficos
Autores principales: Lv, Yinghua, Li, Tianjiao, Yang, Manman, Su, Lihong, Zhu, Zhendong, Zhao, Sihang, Zeng, Wenxian, Zheng, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212693/
https://www.ncbi.nlm.nih.gov/pubmed/34150779
http://dx.doi.org/10.3389/fcell.2021.684398