Helenalin Facilitates Reactive Oxygen Species-Mediated Apoptosis and Cell Cycle Arrest by Targeting Thioredoxin Reductase-1 in Human Prostate Cancer Cells

BACKGROUND: Helenalin is a pseudoguaianolide natural product with anti-cancer activities. This study investigated the underlying mechanism of the anti-prostate cancer effects of helenalin in vitro. MATERIAL/METHODS: CCK-8 assay was performed to detect the optimal concentrations of helenalin in DU145...

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Detalles Bibliográficos
Autores principales: Yang, Mei, Zhang, Weihua, Yu, Xiuxiu, Wang, Feng, Li, Yeping, Zhang, Yan, Yang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212699/
https://www.ncbi.nlm.nih.gov/pubmed/34125740
http://dx.doi.org/10.12659/MSM.930083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212699/
https://www.ncbi.nlm.nih.gov/pubmed/34125740
http://dx.doi.org/10.12659/MSM.930083

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