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Helenalin Facilitates Reactive Oxygen Species-Mediated Apoptosis and Cell Cycle Arrest by Targeting Thioredoxin Reductase-1 in Human Prostate Cancer Cells

BACKGROUND: Helenalin is a pseudoguaianolide natural product with anti-cancer activities. This study investigated the underlying mechanism of the anti-prostate cancer effects of helenalin in vitro. MATERIAL/METHODS: CCK-8 assay was performed to detect the optimal concentrations of helenalin in DU145...

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Detalles Bibliográficos
Autores principales:	Yang, Mei, Zhang, Weihua, Yu, Xiuxiu, Wang, Feng, Li, Yeping, Zhang, Yan, Yang, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2021
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212699/ https://www.ncbi.nlm.nih.gov/pubmed/34125740 http://dx.doi.org/10.12659/MSM.930083

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