A Randomized Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Recombinant Erwinia Asparaginase (JZP‐458) in Healthy Adult Volunteers

L‐asparaginase has been an important component of acute lymphoblastic leukemia (ALL) therapy for over 40 years, and is standard therapy during ALL induction and consolidation treatment. L‐asparaginases are immunogenic and can induce hypersensitivity reactions; inability to receive asparaginase has b...

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Detalles Bibliográficos
Autores principales: Lin, Tong, Hernandez‐Illas, Martha, Rey, Andres, Jenkins, Jack, Chandula, Reddy, Silverman, Jeffrey A., Choi, Mi Rim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212713/
https://www.ncbi.nlm.nih.gov/pubmed/33278328
http://dx.doi.org/10.1111/cts.12947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212713/
https://www.ncbi.nlm.nih.gov/pubmed/33278328
http://dx.doi.org/10.1111/cts.12947

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