A target‐mediated drug disposition population pharmacokinetic model of GC1118, a novel anti‐EGFR antibody, in patients with solid tumors

ABSTRACT: GC1118 is a monoclonal antibody for epidermal growth factor receptor (EGFR) that is currently under clinical development to treat patients with solid tumors. In this study, the pharmacokinetics (PKs) of GC1118 were modeled in solid tumor patients who received a 2‐h intravenous infusion of...

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Detalles Bibliográficos
Autores principales: Chung, Tae Kyu, Lee, Hyun A., Park, Sang‐In, Oh, Do‐Youn, Lee, Keun‐Wook, Kim, Jin Won, Kim, Jee Hyun, Woo, Ahmi, Lee, Su Jin, Bang, Yung‐Jue, Lee, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212746/
https://www.ncbi.nlm.nih.gov/pubmed/33382918
http://dx.doi.org/10.1111/cts.12963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212746/
https://www.ncbi.nlm.nih.gov/pubmed/33382918
http://dx.doi.org/10.1111/cts.12963

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