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Probability of pharmacological target attainment with flucloxacillin in Staphylococcus aureus bloodstream infection: a prospective cohort study of unbound plasma and individual MICs

OBJECTIVES: MSSA bloodstream infections (BSIs) are associated with considerable mortality. Data regarding therapeutic drug monitoring (TDM) and pharmacological target attainment of the β-lactam flucloxacillin are scarce. PATIENTS AND METHODS: We determined the achievement of pharmacokinetic/pharmaco...

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Detalles Bibliográficos
Autores principales: Moser, Stephan, Rehm, Sophia, Guertler, Nicolas, Hinic, Vladimira, Dräger, Sarah, Bassetti, Stefano, Rentsch, Katharina M, Sendi, Parham, Osthoff, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212765/
https://www.ncbi.nlm.nih.gov/pubmed/33860325
http://dx.doi.org/10.1093/jac/dkab089