Cargando…

Probability of pharmacological target attainment with flucloxacillin in Staphylococcus aureus bloodstream infection: a prospective cohort study of unbound plasma and individual MICs

OBJECTIVES: MSSA bloodstream infections (BSIs) are associated with considerable mortality. Data regarding therapeutic drug monitoring (TDM) and pharmacological target attainment of the β-lactam flucloxacillin are scarce. PATIENTS AND METHODS: We determined the achievement of pharmacokinetic/pharmaco...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moser, Stephan, Rehm, Sophia, Guertler, Nicolas, Hinic, Vladimira, Dräger, Sarah, Bassetti, Stefano, Rentsch, Katharina M, Sendi, Parham, Osthoff, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212765/ https://www.ncbi.nlm.nih.gov/pubmed/33860325 http://dx.doi.org/10.1093/jac/dkab089

Ejemplares similares

High unbound flucloxacillin fraction in critically ill patients
por: Wallenburg, Eveline, et al.
Publicado: (2021)

Paclitaxel, Imatinib and 5-Fluorouracil Increase the Unbound Fraction of Flucloxacillin In Vitro
por: Stolte, Maximilian, et al.
Publicado: (2020)

Optimization of flucloxacillin dosing regimens in critically ill patients using population pharmacokinetic modelling of total and unbound concentrations
por: Jager, Nynke G L, et al.
Publicado: (2020)

Target attainment and population pharmacokinetics of flucloxacillin in critically ill patients: a multicenter study
por: Meenks, Sjoerd D., et al.
Publicado: (2023)

Identification of flucloxacillin-modified hepatocellular proteins: implications in flucloxacillin-induced liver injury
por: Ali, Serat-E, et al.
Publicado: (2023)

Targeting thromboinflammation in COVID-19 – A narrative review of the potential of C1 inhibitor to prevent disease progression
por: Urwyler, Pascal, et al.
Publicado: (2022)

Early Target Attainment With Continuous Infusion Meropenem and Piperacillin/Tazobactam and Utilization of Therapeutic Drug Monitoring in Critically Ill Patients: A Retrospective Cohort Study From 2017 to 2020
por: Dräger, Sarah, et al.
Publicado: (2023)

Flucloxacillin and paracetamol induced pyroglutamic acidosis
por: Zand Irani, Anis, et al.
Publicado: (2021)

Escherichia coli bloodstream infection preceding the diagnosis of rectal carcinoma
por: Thoma, Reto, et al.
Publicado: (2018)

Discrepancy in Vancomycin AUC/MIC Ratio Targeted Attainment Based upon the Susceptibility Testing in Staphylococcus aureus
por: Eum, Seenae, et al.
Publicado: (2016)

Oral Flucloxacillin for Staphylococcal Osteomyelitis: Obsolete or Underused?
por: Tevell, Staffan, et al.
Publicado: (2020)

Oral flucloxacillin and phenoxymethylpenicillin versus flucloxacillin alone for the emergency department outpatient treatment of cellulitis: study protocol for a randomised controlled trial
por: Quirke, Michael, et al.
Publicado: (2013)

Bile Nephropathy in Flucloxacillin-Induced Cholestatic Liver Dysfunction
por: Alnasrallah, Basil, et al.
Publicado: (2016)

Broad-spectrum azoles and flucloxacillin: a dangerous match
por: Vangheluwe, Tine, et al.
Publicado: (2021)

Concomitant Treatment with Voriconazole and Flucloxacillin: A Combination to Avoid
por: Van Daele, Ruth, et al.
Publicado: (2021)

2533. Cerebrospinal Fluid Penetration of Cefazolin and Flucloxacillin in Children
por: Boast, Alison, et al.
Publicado: (2023)

Treatment of COVID-19 With Conestat Alfa, a Regulator of the Complement, Contact Activation and Kallikrein-Kinin System
por: Urwyler, Pascal, et al.
Publicado: (2020)

Mathematics unbound
por: Parshall, Karen Hunger, et al.
Publicado: (2002)

High MICs for Vancomycin and Daptomycin and Complicated Catheter-Related Bloodstream Infections with Methicillin-Sensitive Staphylococcus aureus
por: San-Juan, Rafael, et al.
Publicado: (2016)

Cefiderocol for Extensively Drug-Resistant Gram-Negative Bacterial Infections: Real-world Experience From a Case Series and Review of the Literature
por: Zingg, Sandra, et al.
Publicado: (2020)

Intravenous flucloxacillin treatment is associated with a high incidence of hypokalaemia
por: van der Heijden, Charlotte D.C.C., et al.
Publicado: (2019)

Swedish multicentre study of target attainments with β-lactams in the ICU: which MIC parameter should be used?
por: Smekal, Anna-Karin, et al.
Publicado: (2023)

Potentials Unbounded Below
por: Curtright, Thomas
Publicado: (2010)

Biased computation of probability of target attainment for antimicrobial drugs
por: Toutain, Pierre‐Louis, et al.
Publicado: (2023)

Characterization of Flucloxacillin-specific CD8+ T-cells in a mouse model
por: Nattrass, Ryan, et al.
Publicado: (2014)

Clinical factors predicting drug-induced liver injury due to flucloxacillin
por: Lindh, Mikaela, et al.
Publicado: (2018)

Oral Flucloxacillin for Treating Osteomyelitis: A Narrative Review of Clinical Practice
por: Preiss, Helga, et al.
Publicado: (2020)

Flucloxacillin/paracetamol: High-anion gap metabolic acidosis : case report
Publicado: (2021)

Ethnography unbound : power and resistance in the modern metropolis /
Publicado: (1991)

124. Impact of Levofloxacin MIC on Outcomes with Levofloxacin Step-down Therapy in Enterobacteriaceae Bloodstream Infections
por: White, Melissa, et al.
Publicado: (2019)

Unbounded linear operators : theory and applications
por: Goldberg, Seymour 1928-
Publicado: (1996)

Bacteriophages Combined With Subtherapeutic Doses of Flucloxacillin Act Synergistically Against Staphylococcus aureus Experimental Infective Endocarditis
por: Save, Jonathan, et al.
Publicado: (2022)

Pharmacokinetic/Pharmacodynamic Target Attainment Based on Measured versus Predicted Unbound Ceftriaxone Concentrations in Critically Ill Patients with Pneumonia: An Observational Cohort Study
por: Gijsen, Matthias, et al.
Publicado: (2021)

Unbound states in quantum heterostructures
por: Ferreira, R, et al.
Publicado: (2006)

Unbounding the future: the nanotechnology revolution
por: Drexler, Eric K, et al.
Publicado: (1991)

Unbounded non-commutative integration
por: Jurzak, J P
Publicado: (1985)

Unbounded solutions of models for glycolysis
por: Brechmann, Pia, et al.
Publicado: (2021)

Geography unbound : French geographic science from Cassini to Humboldt /
por: Godlewska, Anne
Publicado: (1999)

1302. Cefiderocol Population Pharmacokinetics and Probability of Target Attainment in Plasma and Epithelial Lining Fluid in Patients with Pneumonia, Bloodstream Infection/Sepsis, or Complicated Urinary Tract Infections
por: Katsube, Takayuki, et al.
Publicado: (2020)

Factors impacting the pre-analytical quality of blood cultures—Analysis at a tertiary medical center
por: Romann, Lucas, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mm6decno1iaokr239lf355qihh