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Group A streptococcal antigen exposed rat model to investigate neurobehavioral and cardiac complications associated with post‐streptococcal autoimmune sequelae

BACKGROUND: The neuropsychiatric disorders due to post‐streptococcal autoimmune complications such as Sydenham's chorea (SC) are associated with acute rheumatic fever and rheumatic heart disease (ARF/RHD). An animal model that exhibits characteristics of both cardiac and neurobehavioral defects...

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Detalles Bibliográficos
Autores principales: Rafeek, Rukshan A. M., Lobbe, Catherine M., Wilkinson, Ethan C., Hamlin, Adam S., Andronicos, Nicholas M., McMillan, David J., Sriprakash, Kadaba S., Ketheesan, Natkunam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212825/
https://www.ncbi.nlm.nih.gov/pubmed/34179722
http://dx.doi.org/10.1002/ame2.12164