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In silico comparative analysis of LRRK2 interactomes from brain, kidney and lung

Mutations in LRRK2 are the most frequent cause of familial Parkinson’s disease (PD), with common LRRK2 non-coding variants also acting as risk factors for idiopathic PD. Currently, therapeutic agents targeting LRRK2 are undergoing advanced clinical trials in humans, however, it is important to under...

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Detalles Bibliográficos
Autores principales: Verma, Amrita, Ebanks, Kirsten, Fok, Chi-Yee, Lewis, Patrick A., Bettencourt, Conceicao, Bandopadhyay, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212912/
https://www.ncbi.nlm.nih.gov/pubmed/33915162
http://dx.doi.org/10.1016/j.brainres.2021.147503