SARS-CoV-2 Spike Protein Suppresses ACE2 and Type I Interferon Expression in Primary Cells From Macaque Lung Bronchoalveolar Lavage

SARS-CoV-2 virus causes upper and lower respiratory diseases including pneumonia, and in some cases, leads to lethal pulmonary failure. Angiotensin converting enzyme-2 (ACE2), the receptor for cellular entry of SARS-CoV-2 virus, has been shown to protect against severe acute lung failure. Here, we p...

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Detalles Bibliográficos
Autores principales: Sui, Yongjun, Li, Jianping, Venzon, David J., Berzofsky, Jay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213020/
https://www.ncbi.nlm.nih.gov/pubmed/34149696
http://dx.doi.org/10.3389/fimmu.2021.658428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213020/
https://www.ncbi.nlm.nih.gov/pubmed/34149696
http://dx.doi.org/10.3389/fimmu.2021.658428

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