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FHL3 Contributes to EMT and Chemotherapy Resistance Through Up-Regulation of Slug and Activation of TGFβ/Smad-Independent Pathways in Gastric Cancer

BACKGROUND: Gastric cancer presents high risk of metastasis and chemotherapy resistance. Hence, it is important to understand the mechanisms of gastric cancer distant metastasis and chemotherapeutic resistance. Our previous study has revealed Four and a Half LIM Domains 3 (FHL3) plays as a binding p...

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Detalles Bibliográficos
Autores principales: Cao, Guodong, Li, Pengping, He, Xiaobo, Jin, Mengyao, Li, Mengying, Chen, Sihan, Xu, Xin, Sun, Qiang, Xiong, Maoming, Chen, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213027/
https://www.ncbi.nlm.nih.gov/pubmed/34150617
http://dx.doi.org/10.3389/fonc.2021.649029