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The effect of caloric restriction on the increase in senescence-associated T cells and metabolic disorders in aged mice

Aging is associated with functional decline in the immune system and increases the risk of chronic diseases owing to smoldering inflammation. In the present study, we demonstrated an age-related increase in the accumulation of Programmed Death-1 (PD-1)(+) memory-phenotype T cells that are considered...

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Detalles Bibliográficos
Autores principales: Yan, Xiaoxiang, Imano, Natsumi, Tamaki, Kayoko, Sano, Motoaki, Shinmura, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213184/
https://www.ncbi.nlm.nih.gov/pubmed/34143796
http://dx.doi.org/10.1371/journal.pone.0252547