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The effect of caloric restriction on the increase in senescence-associated T cells and metabolic disorders in aged mice
Aging is associated with functional decline in the immune system and increases the risk of chronic diseases owing to smoldering inflammation. In the present study, we demonstrated an age-related increase in the accumulation of Programmed Death-1 (PD-1)(+) memory-phenotype T cells that are considered...
Autores principales: | Yan, Xiaoxiang, Imano, Natsumi, Tamaki, Kayoko, Sano, Motoaki, Shinmura, Ken |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213184/ https://www.ncbi.nlm.nih.gov/pubmed/34143796 http://dx.doi.org/10.1371/journal.pone.0252547 |
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