Intestinal iron absorption is appropriately modulated to match physiological demand for iron in wild-type and iron-loaded Hamp (hepcidin) knockout rats during acute colitis

Mucosal damage, barrier breach, inflammation, and iron-deficiency anemia (IDA) typify ulcerative colitis (UC) in humans. The anemia in UC appears to mainly relate to systemic inflammation. The pathogenesis of this ‘anemia of inflammation’ (AI) involves cytokine-mediated transactivation of hepatic Ha...

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Detalles Bibliográficos
Autores principales: Flores, Shireen R. L., Nelson, Savannah, Woloshun, Regina R., Wang, Xiaoyu, Ha, Jung-Heun, Lee, Jennifer K., Yu, Yang, Merlin, Didier, Collins, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213193/
https://www.ncbi.nlm.nih.gov/pubmed/34143808
http://dx.doi.org/10.1371/journal.pone.0252998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213193/
https://www.ncbi.nlm.nih.gov/pubmed/34143808
http://dx.doi.org/10.1371/journal.pone.0252998

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