p53 loss activates prometastatic secretory vesicle biogenesis in the Golgi

Cancer cells exhibit hyperactive secretory states that maintain cancer cell viability and remodel the tumor microenvironment. However, the oncogenic signals that heighten secretion remain unclear. Here, we show that p53 loss activates prometastatic secretory vesicle biogenesis in the Golgi. p53 loss...

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Detalles Bibliográficos
Autores principales: Tan, Xiaochao, Banerjee, Priyam, Shi, Lei, Xiao, Guan-Yu, Rodriguez, B. Leticia, Grzeskowiak, Caitlin L., Liu, Xin, Yu, Jiang, Gibbons, Don L., Russell, William K., Creighton, Chad J., Kurie, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213221/
https://www.ncbi.nlm.nih.gov/pubmed/34144984
http://dx.doi.org/10.1126/sciadv.abf4885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213221/
https://www.ncbi.nlm.nih.gov/pubmed/34144984
http://dx.doi.org/10.1126/sciadv.abf4885

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