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Activation mechanism of Drosophila cryptochrome through an allosteric switch

Cryptochromes are signaling proteins activated by photoexcitation of the flavin adenine dinucleotide (FAD) cofactor. Although extensive research has been performed, the mechanism for this allosteric process is still unknown. We constructed three computational models, corresponding to different redox...

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Detalles Bibliográficos
Autores principales: Wang, Yingjie, Veglia, Gianluigi, Zhong, Dongping, Gao, Jiali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213227/
https://www.ncbi.nlm.nih.gov/pubmed/34144991
http://dx.doi.org/10.1126/sciadv.abg3815