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Activation mechanism of Drosophila cryptochrome through an allosteric switch
Cryptochromes are signaling proteins activated by photoexcitation of the flavin adenine dinucleotide (FAD) cofactor. Although extensive research has been performed, the mechanism for this allosteric process is still unknown. We constructed three computational models, corresponding to different redox...
Autores principales: | Wang, Yingjie, Veglia, Gianluigi, Zhong, Dongping, Gao, Jiali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213227/ https://www.ncbi.nlm.nih.gov/pubmed/34144991 http://dx.doi.org/10.1126/sciadv.abg3815 |
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