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Structural insights into the recognition of histone H3Q5 serotonylation by WDR5

Serotonylation of histone H3Q5 (H3Q5ser) is a recently identified posttranslational modification of histones that acts as a permissive marker for gene activation in synergy with H3K4me3 during neuronal cell differentiation. However, any proteins that specifically recognize H3Q5ser remain unknown. He...

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Detalles Bibliográficos
Autores principales: Zhao, Jie, Chen, Wanbiao, Pan, Yi, Zhang, Yinfeng, Sun, Huiying, Wang, Han, Yang, Fan, Liu, Yu, Shen, Nan, Zhang, Xuan, Mo, Xi, Zang, Jianye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213231/
https://www.ncbi.nlm.nih.gov/pubmed/34144982
http://dx.doi.org/10.1126/sciadv.abf4291